NSAIDs demper denne reaksjonen ved å hindre dannelse av en gruppe betennelsesfremkallende stoffer kalt prostaglandiner. Denne effekten kan være svært gunstig ved smerter i muskel og skjelett eller andre smertetyper hvor betennelse er en viktig årsak til smerten. Etter å ha dominert markedet for smertestillende medisiner i sixty år, fikk
This points out why just one lorazepam dose, Inspite of its shorter serum 50 %-lifetime, has additional prolonged peak outcomes than an equal diazepam dose.[ninety nine] Lorazepam is speedily conjugated at its 3-hydroxy group into lorazepam glucuronide and that is then excreted within the urine. Lorazepam glucuronide has no demonstrable CNS action
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